The study has many even more limitations. For the United states and you will HK cohorts, new intent was to generate “normal” ambulatory lady without secondary factors behind osteoporosis. Whilst the employment standards total were quite similar, the criteria differed slightly towards All of us cohort having so much more specific different standards. The greater number of “stringent” exclusion conditions in the usa cohort could bias into shopping for most useful microarchitecture inside the Chinese Us americans and you may light ladies in the place of the latest Chinese females from inside the HK. Once the our efficiency essentially work on counter compared to that expectation, the audience is reassured that the isn’t a major way to obtain bias. In addition, the same results anywhere between our results and those out-of almost every other Asian cohorts highly recommend this new conclusions are likely to be generalizable.

Another restrict is the real difference within the try size involving the cohorts. (suite…)